People with Chronic Diseases
Medical weight loss treatment for obesity with metabolic syndrome: from standard diagnosis to comprehensive intervention
This article systematically introduces the clinical assessment and medical intervention for obesity combined with metabolic syndrome (MS). It compares various MS diagnostic criteria, including those from the WHO, NCEP-ATP III, and IDF, and focuses on the risk warning role of abdominal obesity in type 2 diabetes and cardiovascular disease. A comprehensive treatment pathway is proposed,...
2026-03-29Metabolic Disorders and Weight Loss Treatment in Polycystic Ovary Syndrome: Clinical Diagnosis, Lifestyle and Adjunctive Interventions
This article comprehensively explores the pathophysiological characteristics and clinical diagnostic criteria of polycystic ovary syndrome (PCOS). It analyzes in detail the crucial role of weight loss in restoring ovulation and improving metabolism, and provides systematic guidance on drug treatment, including calorie-restricted diets, ketogenic diets, exercise, and medications such as...
2026-03-29Metabolic factors that induce tumor development: obesity, insulin resistance, and the carcinogenic mechanism of adipokines
This article delves into the complex molecular mechanisms by which obesity contributes to increased cancer incidence. It explores how low-grade inflammation in adipose tissue, oxidative stress, peripheral insulin resistance, and dyslipidemia collectively promote tumorigenesis. The article focuses on the energy support provided by a hyperglycemic environment for tumor cell proliferation, and...
2026-03-28Obesity and Cardiovascular Health: From Pathophysiology to Comprehensive Intervention Strategies
This article details the impact of obesity as a core risk factor for cardiovascular disease and its pathophysiological mechanisms. It explores how obesity triggers hypertension, coronary heart disease, and stroke through pathways such as sympathetic hyperactivity, insulin resistance, and oxidative stress, and describes the corresponding clinical manifestations. Finally, the article proposes a...
2026-03-27Obesity and its relationship with endocrine metabolism, mental health, and diagnostic criteria
This study integrates the endocrine disorders and mental health challenges caused by obesity, as well as the various indicators and data ranges used in clinical practice to scientifically assess the degree of obesity.
2026-03-27The pathophysiological mechanisms of obesity and the brain-gut axis theory
This study deconstructs the genetic, environmental, and endocrine physiological mechanisms of obesity, focusing on the complex bidirectional regulatory system between gut microbiota, the HPA axis, and the nervous system.
2026-03-27Carbohydrate metabolism in obese individuals: insulin resistance and impaired glucose utilization
This article delves into the close relationship between obesity and altered carbohydrate metabolism. It details how elevated free fatty acids (FFA) act as a central event in metabolic disorders, triggering hepatic gluconeogenesis and systemic insulin resistance. The article focuses on the role of skeletal muscle in obesity-related metabolic abnormalities and how hyperinsulinemia promotes fat...
2026-03-27Obesity-related chronic diseases: cardiovascular and metabolic diseases
This paper systematically explains how obesity, as the core of "obesity-related chronic diseases (ABCD)," induces a series of clinical complications such as hypertension, coronary heart disease, diabetes, and metabolic syndrome.
2026-03-27Lucaso's weight loss revolution: Achieving metabolic transformation through blood sugar control and complete nutrition supplementation.
This article details the core theory of the Lucaso weight loss method. By limiting refined rice and flour, often considered "the four evils of weight loss," it controls blood sugar fluctuations and corrects insulin resistance, thereby shutting down fat synthesis. The article further elucidates the standards for Lucaso nutritional foods and introduces the dual protection concept of...
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